Fenasetin
Fenasetin CAS:62-44-2
Fenasetin Chemical Properties
MF: C10H13NO2
MW: 179.22
Titik lebur: 133-136 ° C (lit.)
Takat didih: 132 ° C / 4mmHg
Ketumpatan: 1.1248 (anggaran kasar)
Fenasetin Specification:
Uji% â ‰ ¥ 99.0
klorida organik% â ‰ ¤0.02
p-Phenetidineâ ‰ redlight redã € 4 #
Sebatian karbon mudah ‰ #4 # ã € 6 #
Kerugian pengeringan% â ‰ ¤0.5
Takat lebur: 134-137oC
Sisa pencucuhan% â ‰ ¤0.1
Fenasetin Introduction:
Fenasetin is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenasetin is a pain-relieving and fever-reducing drug,
Fenasetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.
This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenasetin has been linked to renal papillary necrosis in human beings [2, 3].
Fenasetin Application:
Analgesik antipiretik, digunakan untuk rawatan demam, sakit kepala, neuralgia, dan lain-lain
